I would recommend:
Trouble with Modules and World Size Check first of all.
But, if you want general rules:
No huuuge maps. Break them up if you can.
Cut down on Modules, especially once like FX master or such.
If your world is Huge (see links above) cut down on the files that are high. We’ve seen extreme amounts of actors and such. Delete them or put them in a compendium.
Clear out chat as often as you can. (I usually do it once after every game.) Rolls like 600d100000000 will crash people.
That should be the basics, hope your your next game goes better ^^
If anything else feel free to post here and I’ll follow up.